ABSTRACT
COVID-19 has been distinguished as a zoonotic coronavirus, like SARS coronavirus and MERS coronavirus. Tehran metropolis, as the capital of Iran, has a high density of residents that experienced a high incidence and mortality rates which daily increase the number of death and cases. In this study, the IDW (Inverse Distance Weight), Hotspots, and GWR (Geography Weighted Regression) Model are used as methods for analyzing big data COVID-19 in Tehran. The results showed that the majority of patients and deaths were men, but the death rate was higher in women than in men; also was observed a direct relationship between the area of the houses, and the infected rate, to COVID-19. Also, the results showed a disproportionate distribution of patients in Tehran, although in the eastern regions the number of infected people is higher than in other districts; the eastern areas have a high population density as well as residential land use, and there is a high relationship between population density in residential districts and administrative-commercial and the number of COVID-19 cases in all regions. The outputs of local R2 were interesting among patients and underlying disorders; the local R2 between hypertension and neurological diseases was 0.91 and 0.79, respectively, which was higher than other disorders. The highest rates of local R2 for diabetes and heart disease were 0.67 and 0.55, respectively. From this study, it can be concluded the restrictions must be considered especially, in areas densely populated for all people.
ABSTRACT
Background and purpose: Coronavirus disease (COVID-19) causes different symptoms. Mizaj or temperament in Persian traditional medicine is a specific feature of every human being. The aim of this study was to determine the relationship between Mizaj and severity of symptoms in patients with COVID-19. Materials and methods: A descriptive correlational study was performed in patients with symptomatic COVID-19 during recovery and interviews were carried out to record patients' symptoms (fever, cough, chills, etc.). Salmannezhad Mizaj questionnaire was used to determine the patients' temperament (warm, cold, wet, and dry). The number of symptoms in each patient was determined and the severity of symptoms was classified into three levels: mild, moderate, and severe. The relationship between Mizaj and COVID-19 clinical symptoms were assessed by Chi-square and Pearson correlation coefficients.
ABSTRACT
Background and purpose: Coronavirus disease (COVID-19) causes different symptoms. Mizaj or temperament in Persian traditional medicine is a specific feature of every human being. The aim of this study was to determine the relationship between Mizaj and severity of symptoms in patients with COVID-19. Materials and methods: A descriptive correlational study was performed in patients with symptomatic COVID-19 during recovery and interviews were carried out to record patients’ symptoms (fever, cough, chills, etc.). Salmannezhad Mizaj questionnaire was used to determine the patients’ temperament (warm, cold, wet, and dry). The number of symptoms in each patient was determined and the severity of symptoms was classified into three levels: mild, moderate, and severe. The relationship between Mizaj and COVID-19 clinical symptoms were assessed by Chi-square and Pearson correlation coefficients. Results: In this study, 168 patients (48 ± 13.3 years) were cared for between 4 and 30 days in COVID Recovery Center. Fever, dyspnea, and cough were seen in 73.2%. Among the patients, 47.6% had cold Mizaj and 26.2% had warm or moderate Mizaj. The frequency of severe symptoms was higher in patients with cold Mizaj compared with that in patients with warm or moderate Mizaj (P= 0.204). Myalgia was found to be considerably higher in cold-Mizaj patients than warm-Mizaj people (P= 0.006). Significant correlations were seen between wet and dry Mizaj and severity of symptoms (P<0.046, R= 0.554) and warm and cold Mizaj and frequency of symptoms (P< 0.054, R= 0.489). Conclusion: Patients with COVID-19, who had cold or wet Mizaj had more symptoms, therefore, support, care, and preventive measures of Persian traditional medicine are recommended for people with cold or wet Mizaj exposed to Coronavirus.
ABSTRACT
Since December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged and spread quickly worldwide. The disease is generally mild in adult people but in any with comorbidities may proceed to acute respiratory distress syndrome (ARDS), pneumonia, and multi-organ dysfunction. By performing molecular tests on respiratory secretions can diagnose the virus. Elevated C-reactive protein (CRP) and normal/low white cell counts are common laboratory diagnoses of COVID-19 while the tomographic chest scan is usually irregular for many infected people. Some patients progress to respiratory failure, pneumonia, and finally death by the end of the first week of illness because of the sharp rise in inflammatory cytokines such as IL7, IL2, GCSF, IL10, MIP1A, MCP1, IP10, and TNFα. Various approaches to the COVID- 19 are being performed by scientists. Use of chemical medical drugs that are effective for other viral infections. Among them, remdesivir was approved by FDA on 1th May 2020 because of its impact to treat patients. Also, several studies have revealed that many Chinese herbal remedies have a remarkable impact on the healing process when simultaneously were used along with pharmacological drugs. In the meantime, many efforts have been made to produce an effective vaccine, and so far, the Ad5-vectored COVID-19 vaccine has been successful and has entered phase 2 in the human trial. The current review focus on epidemiology, virology, clinical features, diagnosis, and available treatment of coronavirus that might assist researchers and clinicians in establishing action options for timely against this infection.
ABSTRACT
On December 31, 2019, the Wuhan-China Health Commission reported a case of pneumonia in the city. The first symptoms began in mid-December 2019. Clinically isolated specimens identified the coronavirus as the cause of the disease. It was first shown as 2019-nCoV, and as the number of victims of the coronavirus crossed the border of thousands of people, the World Health Organization chose the official name COVID-19 for its illness. Although it appears to be of animal origin, it is rapidly transmitting from person to person around the world. The World Health Organization released a statement calling the outbreak of the new Corona virus a Public Health Emergency Situations that poses a threat to the whole world, not just China. In this study highlights how the virus is transmitted, the clinical signs, the laboratory characteristics, the pathogenicity of the virus, Vaccines, and the prevention and control of the spread of the virus.